We know that testosterone has a wide-range of effects in men. But how long after you begin testosterone replacement therapy until the testosterone treatment's maximum effects are achieved? The Scientific Affairs team at Men's Healthcare in Germany recently asked that same question, and their results were quite interesting.
With testosterone replacement therapy, effects with sexual interest appear after three weeks, and plateau at six weeks, with no further increments expected beyond. Changes in erections/ejaculations may require up to 6 months of testosterone replacement therapy. Effects on quality of life manifest within 3-4 weeks, but maximum benefits take longer. Effects on depressive mood become detectable after 3-6 weeks with a maximum after 18-30 weeks. Effects on erythropoiesis (the process by which red blood cells are produced) are evident at three months, peaking at 9-12 months. Prostate-specific antigen and volume rise, marginally, plateauing at 12 months; further increase should be related to aging rather than testosterone replacement therapy. Effects on lipids appear after four weeks, maximal after 6-12 months. Insulin sensitivity may improve within few days, but effects on glycemic control become evident only after 3-12 months. Changes in fat mass, lean body mass, and muscle strength occur within 12-16 weeks, stabilize at 6-12 months, but can marginally continue over the years. Effects on inflammation occur within 3-12 weeks. Effects on bone are detectable already after six months while continuing for at least for three years. Read the full study here.
These results show that while the effectiveness time with testosterone replacement therapy varies from symptom to symptom, it does take only a short time to see improvements compared to dealing with the effects of low testosterone for a lifetime. Do you have questions about Testosterone Replacement Therapy? Get them answered here!
Testosterone Replacement Therapy
Low testosterone can be easily diagnosed with a simple blood test and treated with testosterone replacement therapy to bring your testosterone levels back to normal. The testosterone replacement therapy options available are:
- Intramuscular injections
- Sublingual troches that are taken daily
- Testosterone cream that is applied daily to the shoulders, upper arms, or abdomen
Each of these options provides adequate levels of hormone replacement. Each has side effects and advantages and disadvantages. The choice of hormone replacement therapy is best made with a thorough discussion between you and Dr. Bird. This can be discussed at the free testosterone replacement therapy consultation.