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Common Esters Available for Testosterone Injections

Submitted by Robb Bird on Wed, 05/10/2017 - 05:08

Below is a discussion of common testosterone esters. The primary difference between esters is the rate at which testosterone enters the bloodstream following an injection. A slower release means fewer testosterone injections per year. Testosterone propionate is a fast-acting ester rarely used in TRT (Testosterone Replacement Therapy). Testosterone enanthate and testosterone cypionate are slow-acting injectable forms. They have been the predominant form used for TRT. Testosterone undecanoate is a newly approved form that is very slow-acting.

Testosterone Cypionate

Testosterone cypionate is a slow-acting injectable form of the androgen testosterone. Following deep intramuscular injection, the drug provides a sustained release of testosterone into the bloodstream for up to 2 weeks. Testosterone cypionate possesses a half-life of about 8 days. The most commonly recommended dosing regimen for TRT is is 120 to 160 mg every week or 150 to 200 mg every other week. Typically, 26-52 injections are required per year.

 

Testosterone Enanthate

Similar to testosterone cypionate, testosterone enanthate is a slow-acting injectable form of the androgen testosterone. Following deep intramuscular injection, the drug provides a sustained release of testosterone into the bloodstream for up to 2 weeks. Testosterone enanthate possesses a half-life of 8 days. The most commonly recommended dosing regimen for TRT is is 120 to 160 mg every week or 150 to 200 mg every other week. Typically, 26-52 injections are required per year.

 

Testosterone Propionate

In comparison to testosterone enanthate and testosterone cypionate, testosterone propionate is a faster-acting form of the androgen testosterone. Testosterone propionate possesses a half-life of roughly 2-3 days. Therefore, testosterone propionate does not provide a sustained release. Due to this short half-life, it must be injected every third or fourth day. As a result, it is rarely used for TRT.